Duratia 90

Duratia 90 mg Tablet is a prescription medication containing Dapoxetine 90 mg, manufactured by Fortune Healthcare Pvt. Ltd. Available in strips of 10 tablets, it is a selective serotonin reuptake inhibitor (SSRI) designed to treat premature ejaculation (PE) in men aged 18 to 64 years. It aims to prolong the time to ejaculation and enhance control, improving sexual satisfaction and confidence. The 90 mg dose is not a standard or widely approved dosage for PE treatment and may be used only in specific cases under strict medical supervision due to heightened risks of side effects. Duratia 90 mg is taken on-demand, not daily, and requires a doctor’s prescription. It is not approved for PE treatment in the US but is available in some European and Asian countries, including India, typically at lower doses (30 mg or 60 mg).

Uses

Duratia 90 mg Tablet is used for:

• Treating premature ejaculation (PE) in men aged 18 to 64, increasing intravaginal ejaculation latency time (IELT)

• Improving control over ejaculation to reduce frustration and anxiety associated with rapid ejaculation

• Enhancing sexual satisfaction and confidence during intercourse

• Supporting relationship quality by addressing distress caused by PE

Side Effects

Duratia 90 mg Tablet may cause:

• Common: Dizziness, headache, nausea, fatigue, dry mouth, insomnia, restlessness, anxiety, decreased libido, difficulty concentrating, diarrhea, constipation, sweating, tremor

• Rare: Mood changes, depression, agitation, blurred vision, ringing in the ears, flushing, dyspepsia, rhinitis, erectile dysfunction

• Serious: Severe allergic reactions (e.g., rash, itching, swelling, difficulty breathing), fainting, irregular heartbeat, serotonin syndrome (e.g., fever, tremors, confusion, seizures), suicidal thoughts, severe hypotension

Side effects are likely more frequent and severe with the 90 mg dose compared to 30 mg or 60 mg. Seek immediate medical help for severe symptoms like fainting, chest pain, or signs of serotonin syndrome. Consult a doctor if side effects persist or worsen.

How to Use

• Dosage: Take one 90 mg tablet 1–3 hours before anticipated sexual activity, as prescribed by your doctor. Do not take more than one tablet in 24 hours. The 90 mg dose is non-standard and should only be used if lower doses (30 mg or 60 mg) are ineffective and tolerated.

• Administration: Swallow the tablet whole with a full glass of water to avoid its bitter taste. It can be taken with or without food, but a heavy or high-fat meal may delay its effect slightly.

• Missed Dose: Not applicable, as Duratia is taken on-demand, not daily.

• Overdose: Seek immediate medical help for symptoms like severe dizziness, fainting, nervousness, irregular heartbeat, or seizures. The 90 mg dose significantly increases overdose risks.

How Tablet Works

Dapoxetine, the active ingredient in Duratia 90 mg, is a short-acting SSRI that inhibits the serotonin transporter, increasing serotonin levels in the brain’s synaptic cleft. This enhances serotonin’s action at pre- and postsynaptic receptors, delaying the neural pathways involved in ejaculation. At 90 mg, it may further extend the intravaginal ejaculation latency time (IELT), potentially from ~0.8 minutes to ~3.5 minutes, though data on this dose is limited. Its rapid absorption (peak plasma concentration in 1–2 hours) and short half-life (initial ~1.5 hours, terminal ~17.5 hours) make it suitable for on-demand use rather than daily treatment, unlike other SSRIs used off-label for PE. The higher dose increases efficacy but also side effect risks.

Safety Advice

• Allergies: Avoid if allergic to Dapoxetine or any tablet components (e.g., lactose monohydrate, microcrystalline cellulose, iron oxide yellow).

• Health Conditions: Use with extreme caution in patients with heart conditions (e.g., heart failure, abnormal rhythms), low blood pressure, bleeding/clotting disorders, epilepsy, glaucoma, or a history of mood disorders (e.g., depression, mania, bipolar disorder). Contraindicated in severe liver or kidney disease.

• Drug Interactions: May interact with monoamine oxidase inhibitors (MAOIs), other SSRIs/SNRIs, thioridazine, tramadol, St. John’s wort, nitrates, or lithium, risking serotonin syndrome, heart rhythm issues, or severe hypotension. Inform your doctor of all medications and supplements.

• Pregnancy/Breastfeeding: Not intended for women. Limited data suggest potential risks to infants if used during breastfeeding; consult a doctor.

• Driving: Likely to cause dizziness, drowsiness, or blurred vision at 90 mg; avoid driving or operating machinery until you know how it affects you.

• Alcohol: Strictly avoid alcohol, as it significantly increases the risk of fainting, drowsiness, and other side effects at this higher dose.

• Storage: Store at room temperature (20–25°C) in a dry, dark place, away from moisture, heat, children, and pets. Keep in original packaging until use.

• Children: Not recommended for individuals under 18 years.