AF 400 Tablet (Fluconazole 400 mg)

AF 400 Tablet (Fluconazole 400 mg) is an antifungal medicine containing Fluconazole 400 mg, produced by Systopic Laboratories Pvt. Ltd., India. Supplied as a single tablet in a strip, it is a prescription-only medication used to treat serious fungal and yeast infections in areas like the mouth, throat, lungs, blood, and brain, especially in adults with weakened immune systems.

Uses

• Systemic candidiasis (fungal infections in blood, heart, or organs)
• Cryptococcal meningitis (brain and spinal cord infection)
• Oropharyngeal/esophageal candidiasis (severe thrush)
• Prevention of fungal infections in immunocompromised patients (e.g., HIV/AIDS, chemotherapy, or transplant patients)
• Severe fungal infections resistant to lower doses

Side Effects

• Common: Nausea, headache, stomach pain, diarrhea, rash
• Rare: Dizziness, seizures, liver problems (yellow skin/eyes), severe allergic reactions (rash, swelling), or heart rhythm issues Seek medical help if severe side effects occur.

How to Use

• Dosage:
  • Systemic candidiasis/meningitis: 400 mg on day one, then 200-400 mg daily for weeks, as prescribed.
  • Prevention: 200-400 mg daily, per doctor’s advice.
  • Children/elderly: Doctor adjusts dose; not for kids under 16 unless necessary.
• Swallow with water, with or without food. Take daily at the same time. Complete the full course.
• Overdose: Seek emergency help for symptoms like confusion or hallucinations.

How Tablet Works

Fluconazole blocks ergosterol production, a vital part of fungal cell walls, causing fungi to weaken and die. It starts working within days for some infections, with full effects taking longer for severe cases.

Safety Advice

• Allergies: Avoid if allergic to Fluconazole or azole antifungals.
• Health Conditions: Use cautiously with liver, kidney, or heart issues. Monitor liver function during treatment.
• Drug Interactions: Don’t take with heart rhythm drugs (e.g., amiodarone). Inform your doctor about all medications.
• Pregnancy/Breastfeeding: Avoid in pregnancy due to risk of birth defects. Not advised while breastfeeding; consult a doctor.
• Driving: May cause dizziness; avoid driving if affected.
• Alcohol: May worsen dizziness; check with your doctor.
• Lactose: Contains lactose; avoid if lactose-intolerant.

What If You Forget to Take Tablet?

Take the missed dose as soon as remembered, unless close to the next dose. Don’t double up. Missing doses may reduce effectiveness. Use a reminder to stay consistent.