Cernos Gel is a prescription-only transdermal gel containing Testosterone 1% w/w (10 mg per gram), manufactured by Sun Pharmaceutical Industries Ltd., India. Supplied in 5 gm sachets or tubes, it is used for testosterone replacement therapy in adult men with hypogonadism, a condition where the body produces insufficient testosterone. Applied to the skin, it restores testosterone levels to alleviate symptoms like low libido, fatigue, and muscle loss. It is not for women, children, or men with prostate/breast cancer.
Uses
- Treats male hypogonadism (low testosterone), improving symptoms like impotence, infertility, low sex drive, tiredness, depression, and bone loss
- Manages delayed puberty in adolescent boys (14–17 years) under specialist supervision
- Off-label: May support beard growth, muscle mass, or andropause symptoms (age-related testosterone decline)
Side Effects
- Common: Skin irritation (burning, itching, redness), acne, headache, mood changes, increased red blood cells
- Rare: Frequent erections, weight gain, high blood pressure, prostate issues, liver problems (yellow skin/eyes), severe allergic reactions (hives, swelling) Seek immediate medical help for serious symptoms like shortness of breath or persistent side effects.
How to Use
- Dosage: Apply 5 g (50 mg testosterone) once daily, preferably in the morning, to clean, dry, intact skin on shoulders, upper arms, or abdomen. Adjust dose (2.5–10 g) based on doctor’s advice and testosterone levels. Max: 10 g/day.
- Apply gel, rub gently until dry, then cover with clothing. Wash hands with soap after. Avoid showering/swimming for 5 hours post-application. Do not apply to genitals or broken skin.
- Overdose: Seek emergency help for excessive application or ingestion, which may cause irritability or prolonged erections.
How Gel Works
Cernos Gel delivers synthetic testosterone through the skin, absorbed into the bloodstream to replenish low levels. It binds to androgen receptors, promoting male sexual characteristics, muscle growth, bone density, and mood regulation. Effects on libido may appear in 3 weeks, while erections or muscle changes may take up to 6 months.
Safety Advice
- Allergies: Avoid if allergic to testosterone, soy, or gel ingredients (contains 68.9% ethanol).
- Health Conditions: Contraindicated in prostate/breast cancer, severe heart failure, or high calcium levels. Use cautiously with heart, liver, kidney, lung issues, diabetes, or blood clotting risks. Monitor testosterone, PSA, and liver function regularly.
- Drug Interactions: May enhance anticoagulants (e.g., warfarin) or reduce insulin needs. Inform doctor of all medications.
- Pregnancy/Breastfeeding: Highly unsafe; causes fetal harm (virilization) and toxicity in breastfed infants. Women must avoid contact with application sites.
- Driving: Safe unless dizziness occurs; avoid driving if affected.
- Alcohol: Safety unknown; consult doctor.
- Children: Not for those under 18; accidental exposure may cause early puberty. Keep away from children.
- Precautions: Cover application site to prevent transfer to others, which may cause side effects like excess hair growth in women.
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