Duratia 60

Duratia 60 mg Tablet is a prescription medication containing Dapoxetine 60 mg, manufactured by Fortune Healthcare Pvt. Ltd. Available in strips of 10 tablets, it is a selective serotonin reuptake inhibitor (SSRI) designed to treat premature ejaculation (PE) in men aged 18 to 64 years. It helps prolong the time to ejaculation and enhances control, improving sexual satisfaction and confidence. The 60 mg dose is typically prescribed when the 30 mg dose is insufficient and well-tolerated. Duratia 60 mg is taken on-demand, not daily, and requires a doctor’s prescription due to increased risk of side effects and interactions. It is not approved for PE treatment in the US but is available in several European and Asian countries, including India.

Uses

Duratia 60 mg Tablet is used for:

• Treating premature ejaculation (PE) in men aged 18 to 64, increasing intravaginal ejaculation latency time (IELT)

• Improving control over ejaculation to reduce frustration and anxiety associated with rapid ejaculation

• Enhancing sexual satisfaction and confidence during intercourse

• Supporting relationship quality by addressing distress caused by PE

Side Effects

Duratia 60 mg Tablet may cause:

• Common: Dizziness, headache, nausea, fatigue, dry mouth, insomnia, restlessness, anxiety, decreased libido, difficulty concentrating, diarrhea, constipation, sweating

• Rare: Mood changes, depression, agitation, blurred vision, ringing in the ears, flushing, dyspepsia, rhinitis, erectile dysfunction

• Serious: Severe allergic reactions (e.g., rash, itching, swelling, difficulty breathing), fainting, irregular heartbeat, serotonin syndrome (e.g., fever, tremors, confusion), suicidal thoughts

Side effects may be more pronounced with the 60 mg dose compared to 30 mg. Seek immediate medical help for severe symptoms like fainting, chest pain, or signs of serotonin syndrome. Consult a doctor if side effects persist or worsen.

How to Use

• Dosage: Take one 60 mg tablet 1–3 hours before anticipated sexual activity, as prescribed by your doctor. Do not take more than one tablet in 24 hours.

• Administration: Swallow the tablet whole with a full glass of water to avoid its bitter taste. It can be taken with or without food, but a heavy or high-fat meal may delay its effect slightly.

• Missed Dose: Not applicable, as Duratia is taken on-demand, not daily.

• Overdose: Seek immediate medical help for symptoms like severe dizziness, fainting, nervousness, or irregular heartbeat. The 60 mg dose increases overdose risks compared to lower doses.

How Tablet Works

Dapoxetine, the active ingredient in Duratia 60 mg, is a short-acting SSRI that inhibits the serotonin transporter, increasing serotonin levels in the brain’s synaptic cleft. This enhances serotonin’s action at pre- and postsynaptic receptors, delaying the neural pathways involved in ejaculation. By slowing these pathways, Duratia extends the intravaginal ejaculation latency time (IELT), typically from ~0.8 minutes to ~3.1 minutes at 60 mg, improving control and sexual satisfaction. Its rapid absorption (peak plasma concentration in 1–2 hours) and short half-life (initial ~1.4 hours, terminal ~18.2 hours) make it suitable for on-demand use rather than daily treatment, unlike other SSRIs used off-label for PE.

Safety Advice

• Allergies: Avoid if allergic to Dapoxetine or any tablet components (e.g., lactose monohydrate, microcrystalline cellulose, iron oxide yellow).

• Health Conditions: Use with caution in patients with heart conditions (e.g., heart failure, abnormal rhythms), low blood pressure, bleeding/clotting disorders, epilepsy, glaucoma, or a history of mood disorders (e.g., depression, mania, bipolar disorder). Not recommended for severe liver or kidney disease.

• Drug Interactions: May interact with monoamine oxidase inhibitors (MAOIs), other SSRIs/SNRIs, thioridazine, tramadol, St. John’s wort, nitrates, or lithium, risking serotonin syndrome, heart rhythm issues, or low blood pressure. Inform your doctor of all medications and supplements.

• Pregnancy/Breastfeeding: Not intended for women. Limited data suggest potential risks to infants if used during breastfeeding; consult a doctor.

• Driving: May cause dizziness, drowsiness, or blurred vision; avoid driving or operating machinery until you know how it affects you.

• Alcohol: Avoid alcohol, as it increases the risk of fainting, drowsiness, and other side effects, particularly at the higher 60 mg dose.

• Storage: Store at room temperature (20–25°C) in a dry, dark place, away from moisture, heat, children, and pets. Keep in original packaging until use.

• Children: Not recommended for individuals under 18 years.